Thank you for the review! Little Red was the first thing I made in GameMaker, so feedback like this is valuable (even though I've gotten to it late, haha...).
A good point that you bring up is the fact that there's no incentive in fighting enemies, since they don't drop anything and respawn. I unfortunately don't plan to revisit Little Red, but if I make something like it in the future, incentive to fight is definitely something I'll keep in mind.
As for the game's difficulty, I guess that since it was a game jam, I was in a rush so I didn't properly consider balance. Nor did I really consider how the difficulty would be received by other players, since I consider the difficulty alright - as somebody that's put hundreds of hours into Binding of Isaac, so I guess I just didn't have the same problems.
Looking back, I'm proud of Little Red as a first game kind of thing, but I acknowledge that it's very flawed. Again, I appreciate the feedback!