Well, currently using construct classic, but my netbook is to blame in here. And damn, that must had hurt a lot, I just waste a couple of hours, and notice it has the option to save every 5 minutes that for some reason wasn't active.
I once had an almost completed project flat out stop working whenever I added anything new to the database. This was largely influential in my decision to stop using RM2k3 forever.
RM can be difficult to deal with- a lot of the time (mainly if you're using an old engine) you can just get cheated out of progress.