Checking out the guide, I think I'd be one of the ones that would take over ten hours to complete, since I know nothing about Firefly. I also don't enjoy notation #2 at all. The way the guide comes off to me, it doesn't sound like this game can be any fun unless the player has at least a bit of lore under his or her belt. And that's just to survive, let alone advance.
If the game works even half as much as I suspect it will, this could be totally unplayable to non-fans. I hope this suspicion eventually proves false, though!